Causes of IVF failure
IVF failure is a risk that comes with every cycle of IVF treatment. Sometimes, IVF failure can happen despite the best efforts of the fertility team. Pregnancy can be very complex and if even a tiny deviation from the normal can lead to IVF failure. There are some factors that have been attributed to IVF failure occasionally.
- Egg abnormalities:
Abnormal eggs can be a result of the increased age of the woman or may be dependent on her health history. Certain conditions can cause the cell to have abnormal chromosomes that are prone to breakage resulting in a nonviable embryo.
- Sperm abnormalities
Sperms contribute to a lesser level of IVF failure when compared to eggs. Chromosomally abnormal sperms can lead to lower fertilization rates. In ICSI, chromosomally abnormal sperms can lead to IVF failure too.
- The selection methods of embryo
The fertility specialist that selects the ideal embryo does so keeping three criteria in mind- cell stage, embryo grade, and the rate of cell division. An embryo that has progressed to the 6-8 cell stage are observed to have better chances of developing into pregnancy when compared to 5 or fewer cell stages. Embryos that are of grade 1, 2 are thought to do well after transfer. When an embryo is quick to divide and reaches the 8-cell stage by the third day, it has better chances of doing well than other embryos that have delayed fertilization.
- Egg retrieval
While minor, egg retrieval is still a surgical procedure. This process is very important when it comes to the success of IVF. Retrieving fewer eggs or extracting unsuitable or immature eggs can lead to failure of IVF in the end. Fertility specialists at Oasis are experts at the procedure and have years of experience under their belt. They do everything they can to make sure that the adequate number of usable eggs are retrieved.
- Embryo transfer
Embryo transfer is a sensitive and delicate procedure. The embryo must be transferred to a location in the womb that is optimal for implantation. Cervical mucus or cellular debris can be detrimental to implantation. Any contraction of the mucus muscles can also interfere with the implantation. The fertility experts make sure to have a trial transfer to find out the best place to deposit the embryos. Before the final transfer, they will also remove any cellular debris or cervical mucus that might be interfering with the process. You will be treated with muscle relaxants to ensure that the uterine contractions are prevented. Finally, the embryos are transferred with extreme care and caution to the optimal location.
- IVF laboratory factors
IVF laboratories are a highly controlled environment. Here, the atmosphere of the womb is mimicked to produce the ideal environment for the fertilization and the growth of embryos. The oxygen and carbon dioxide levels are tightly controlled. pH, light temperature and humidity are also kept under control. Even the slightest deviations can lead to IVF failure. Our fertility experts and scientists perform quality control assessments every day. Oasis prides on a Zero- error laboratory that provides the best conditions for embryos to grow and develop.
