IUI Procedure

What is the IUI process or What is the IUI procedure?
The procedure for an IUI treatment cycle is largely determined by two decisions – the type of drugs to be used and the level of monitoring required for the patient. Except for a few minor deviations, largely the process remains the same and is consistent for both types. This is discussed in detail below:

  • Day 1: The first day of IUI cycle for patients who have been placed on hormonal medication, the IUI cycle can begin anytime. However, in case of abnormal uterine wall thickness, a course of progesterone is first administered with causes the onset of periods.
  • Day 2 to 12: This is the phase for the follicles, eggs, and uterine lining to develop. Either this is natural or achieved by medication. In most cases, the medically induced method is preferred, given that it increases the odds of conception. The medications must start 2-4 days following your baseline appointment, with a five-day course of Letrozole and a 10-day course of Gonadatropins.
  • Day 13: Ovulation determination, to ensure that the ovulation is done as close to the date of ovulation as possible. An ultrasound and blood works help determine ovulation. Following this, a trigger shot is administered to ensure ovulation.
  • Day 14: The sperm from the male partner is collected either as a frozen sample that was donated earlier or a fresh unprocessed sample. This will be then prepared for insemination into the uterine cavity with the help of a catheter. Performed without any aesthetic, the insemination procedure is completed in a few minutes.

Following the insemination, there is around a two-week waiting period before the pregnancy can be determined and ascertained. Below is a summary of the various milestones in the IUI process:

Choice of Medication Letrozole is a good alternative but with a comparatively lower success rate, while Gonadotropin improves the success rates but may also come with higher risk profile.
Monitoring & Blood Work This helps doctors understand and ascertain the conditions of the uterus, the possibility of ovulation, and adjust the dosages of medication.
Ovulation In case of triggered ovulation, there is a cost consideration for the patient, but it also ensures there is proper timing and thereby improve the chances of conception.
Sperm Collection A sperm wash is required to remove the damaging elements in a sperm, and it is ideal to use a fresh collection of sperm than a frozen and/shipped variety.

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