Side effects of medication: Medication side effects are usually mild if they occur and they may include hot flashes and mood changes.

Ovarian hyperstimulation syndrome: In some rare cases, a condition called ovarian hyperstimulation syndrome can occur result of which the ovaries may become swollen and cause pain and bloating. Other symptoms may include nausea, vomiting, rapid weight gain due to the accumulation of fluids, shortness of breath, and decreased urine output. In most cases, rest is all that is required to resolve the symptoms. However, in cases where the condition becomes severe, drainage of excess fluid may be necessary.

Multiple gestations: Fertility medications increase the risk of becoming pregnant with multiples from about 3% to 8%. The chance of twins is increased with ovulation induction but the chance of triplets does not increase. The risk of having triplets or more is less than 1%.