Like all medical procedures, assisted hatching involves its share of risks and challenges. Firstly, it is quite possible that in breaking open the shell the embryo itself might suffer irreversible and fatal damage. This may come to light either prior or post the transfer and makes implantation impossible.
Sometimes, the assisted hatching may throw the natural process off and cause failure of the embryo implantation. There is also the risk of identical twins being a by-product of assisted hatching, also higher order pregnancies are equally possible. Finally, some congenital abnormalities have been evidenced in the babies produced from assisted hatching procedure.
The effectiveness of assisted hatching has been achieved in case of those suffering from multiple IVF failures, poor embryo quality, and trying to have a baby much later in their reproductive life.