Magnetic Activated Cell Sorting is an immunogenic procedure wherein sperm with the best characteristics are selected while eliminating those who may have a predisposition to die without achieving fertilization. This involves picking the healthiest sperm and thereby increasing the chances of fertilization pregnancy.

The predisposition to die is known as apoptosis because of their inability to maintain DNA integrity. One of the key elements of sperm health is seminal quality and it affects both fertilization and subsequent embryo quality. Various factors affect semen quality, and the presence of an apoptotic sperm is a crucial one.

MACS is the procedure to remove such sperm by identifying their membranes containing detectable, thereby obtaining a seminal sample free of any apoptotic sperm and excellent quality.